Post by Admin/ Traveler on Nov 18, 2019 19:40:55 GMT
Another wonderful article (and some eye opening statements about what these infections can cause) by Carl Tuttle:
"NOV 18, 2019 —
Today's letter to the Tick-Borne Disease Working Group......
---------- Original Message ----------
From: CARL TUTTLE <runagain@comcast.net>
To: tickbornedisease@hhs.gov, eugene.shapiro@yale.edu
Cc: (98 Undisclosed recipients)
Date: November 18, 2019 at 11:11 AM
Subject: Who is Carl Tuttle?
To: The Tick-Borne Disease Working Group,
ATTN: Eugene Shapiro, MD
The consequences of untreated Lyme disease:
On March 28th 2019 my right kidney was removed (nephrectomy) after a renal scan showed that it was only functioning at 7%. We attempted to save the kidney over the previous 12mo period with a nephrostomy tube by dilating the ureter (Three times unsuccessfully) which was crushed by a large internal lymph node.
Nephrostomy:
www.cirse.org/patients/ir-procedures/nephrostomy/
The swollen lymph node developed as a result of follicular lymphoma which is cancer of the immune system. (Diagnosed in Feb 2017)
In the fall of 2008 I was bedridden, on oxygen and near death after chasing an unresolved fatigue for twelve years. I was ping-ponged through the medical community with deteriorating health and told that I had chronic fatigue syndrome, mitochondrial disease etc. I was forgetting the names of my coworkers of twenty-five years and often did not recognize where I was on my commute home. I was being tested for early Alzheimer's disease. (Similar to Kris Kristofferson)
Carl Tuttle with O2 concentrator:
www.dropbox.com/s/z5918st7pegw4lf/Carl%20Tuttle%20O2%20Concentrator.JPG?dl=0
A Slow Slipping Away Kris Kristofferson’s Long Undiagnosed Battle with Lyme Disease. By Dana Parish
www.lymedisease.org/members/lyme-times/2016-fall-news/kris-kristofferson-lyme-disease/
An astute nurse practitioner advised that I should test for Lyme disease using IGeneX laboratory. Because of the severity of my case it was recommended that I see Dr. Sam Donta of BU School of Medicine who spent a career studying Lyme disease. I Herx’d every day sometimes twice per day for sixteen months. Each time antibiotics were stopped the symptoms would return with a vengeance.
Dr. Donta’s Clinical Notes: (Personal Dropbox storage area)
www.dropbox.com/s/ffvlc9067ei6vd4/Dr%20Donta%20Report%201-26-09.pdf?dl=0
LYME SCI: The dreaded Jarisch-Herxheimer reaction
www.lymedisease.org/lymesci-herxing/
Fast forward to today…. When that large node crushed the right ureter I decided to treat the follicular lymphoma aggressively with Rituxan monotherapy (immunotherapy); my medical claims in 2018 exceeded $600,000. I declined chemotherapy knowing that my immune system was already compromised by the Borrelia infection untreated for twelve years.
Although I uncovered many studies on PubMed noting Borrelia infection together with lymphoma, Dr. Donta felt that my case of lymphoma was more likely a direct result of reactivated Epstein Barr virus which was testing positive on many occasions over the nine years of treatment. A healthy immune system keeps these viruses in check.
Sample EBV lab report: (One of many)
www.dropbox.com/s/iuco0lwurit7a6s/Reactivated%20EBV.JPG?dl=0
Cancer and Infectious Causes
Aaron J. Smith, John Oertle, Dino Prato
Envita, Scottsdale, AZ, USA
Email: Aaron@Envita.com, JohnO@envita.com, DinoPrato@envita.com
Received 4 July 2014; revised 5 August 2014; accepted 4 September 2014
dx.doi.org/10.4236/ojmm.2014.43019
Recently a swollen lymph node in the upper thigh/groin area has returned and a biopsy of that node has identified a more aggressive form of follicular lymphoma. So it looks like the Rituxan has failed. R-CHOP chemotherapy is recommended but the remaining kidney is not functioning at 100% as creatinine levels are elevated and glomerular filtration rate is sub-optimal.
These are the consequences of Lyme disease when the patient is left untreated months, years or decades before diagnosis. But Lyme is a simple “nuisance” disease as dictated by the IDSA and academics that have controlled the narrative for the past thirty years and are now defendants of a racketeering lawsuit in Texas District Court.
Court Document:
www.dropbox.com/s/18uyrli878ug51m/LymeDisease%20RICO%20Lawsuit.pdf?dl=0
What is the motivation for hiding the severity of Lyme disease from the public? Is it just plain ignorance or something more sinister? Lyme disease can be utterly disabling when left untreated but there are no Public Service Announcements informing the public that you could become horribly disabled or die from Lyme disease as exposed in the “Under our Skin” documentary.
Under Our Skin - Extended Trailer (5min video clip)
So I am a Lyme disease victim experiencing exactly what has been outlined (with scientific references) in the following website:
THIS is Lyme
BY BEAUX RELIOSIS on DECEMBER 13, 2017
badlymeattitude.com/2017/12/13/this-is-lyme/
Spirochetes disseminate to the lymph nodes, bone marrow, spleen and brain within a week of infection (1). Lymph node germinal centers, where B cells are supposed to mature and be assigned an immune system function, are rendered incompetent (2). Meanwhile, the toxic triacyl lipoproteins that are shed by spirochetes on blebs of their outer surface get to work causing tolerance and cross tolerance (2,3,4), AKA shutting down the immune system (5,6). There is generalized immune suppression at the same time there are brain inflammation and neurologic complications (7,8,9,10). Opportunistic infections take hold and herpesviruses reactivate (11,12). Half the cases don’t recover fully, regardless of treatment (13,14). The outcome is cancer-like (15, 16).
References: (See personal note at the bottom)
1. Lymphoadenopathy during Lyme Borreliosis Is Caused by Spirochete Migration-Induced Specific B Cell Activation Stefan S. Tunev1,2¤, Christine J. Hastey1,4, Emir Hodzic1, Sunlian Feng1, Stephen W. Barthold, Nicole Baumgarth
www.ncbi.nlm.nih.gov/pmc/articles/PMC3102705/
2. Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection Rebecca A. Elsner, Christine J. Hastey, Kimberly J. Olsen, Nicole Baumgarth Published: July 2, 2015
journals.plos.org/plospathogens/article?id=10.1371%2Fjournal.ppat.1004976
3. J Infect Dis. 2006 Mar 15;193(6):849-59. Epub 2006 Feb 8. Borrelia burgdorferi lipoprotein-mediated TLR2 stimulation causes the down-regulation of TLR5 in human monocytes.
Cabral ES1, Gelderblom H, Hornung RL, Munson PJ, Martin R, Marques AR.
www.ncbi.nlm.nih.gov/pubmed/16479520
4. Borrelia burgdorferi-Induced Tolerance as a Model of Persistence via Immunosuppression
Isabel Diterich1, Carolin Rauter1, Carsten J. Kirschning2 and Thomas Hartung1,*
iai.asm.org/content/71/7/3979.full
5. Lyme Cabal members Gary Wormser and Allen Steere – and even the “CDC officer” Paul Mead – finally admit Late Lyme and LYMErix diseases are immunosuppression outcomes; say “TLR2/1 agonism” (immunosuppression) is probably the “more important” driver of the disease outcome.
Nat Rev Dis Primers. 2016 Dec 15;2:16090. doi: 10.1038/nrdp.2016.90. Lyme borreliosis. Steere AC1,2, Strle F3, Wormser GP4, Hu LT5, Branda JA6, Hovius JW7, Li X8, Mead PS9.
www.ncbi.nlm.nih.gov/pubmed/27976670
6. Seronegative Lyme disease. Dissociation of specific T- and B-lymphocyte responses to Borrelia burgdorferi.
Dattwyler RJ1, Volkman DJ, Luft BJ, Halperin JJ, Thomas J, Golightly MG.
N Engl J Med. 1988 Dec 1;319(22):1441-6.
www.ncbi.nlm.nih.gov/pubmed/3054554
7. Latov, N., Wu, A. T., Chin, R. L., Sander, H. W., Alaedini, A. and Brannagan, T. H. (2004), Neuropathy and cognitive impairment following vaccination with the OspA protein of Borrelia burgdorferi. Journal of the Peripheral Nervous System, 9: 165–167. doi:10.1111/j.1085-9489.2004.09306.x
www.ncbi.nlm.nih.gov/pubmed/15363064
8. Neurological complications of vaccination with outer surface protein A (OspA). Marks DH1. Int J Risk Saf Med. 2011;23(2):89-96. doi: 10.3233/JRS-2011-0527
www.ncbi.nlm.nih.gov/pubmed/21673416
9. J Neuropathol Exp Neurol. 2006 Jun;65(6):540-8. Borrelia burgdorferi Induces TLR1 and TLR2 in human microglia and peripheral blood monocytes but differentially regulates HLA-class II expression.
www.ncbi.nlm.nih.gov/pubmed/16783164
“These results show that signaling through TLR1/2 in response to B. burgdorferi can elicit opposite immunoregulatory effects in blood and in brain immune cells, which could play a role in the different susceptibility of these compartments to infection.”
10. Parthasarathy G, Philipp MT. Receptor tyrosine kinases play a significant role in human oligodendrocyte inflammation and cell death associated with the Lyme disease bacterium Borrelia burgdorferi. Journal of Neuroinflammation. 2017;14:110. doi:10.1186/s12974-017-0883-9.
www.ncbi.nlm.nih.gov/pmc/articles/PMC5450372/
11. Hutchins NA, Unsinger J, Hotchkiss RS, Ayala A. The new normal: immuno-modulatory agents against sepsis immune suppression. Trends in molecular medicine. 2014;20(4):224-233. doi:10.1016/j.molmed.2014.01.002.
www.ncbi.nlm.nih.gov/pmc/articles/PMC3976785/
12. Walton AH, Muenzer JT, Rasche D, Boomer JS, Sato B, et al. (2014) Reactivation of Multiple Viruses in Patients with Sepsis. PLoS ONE 9(6): e98819. doi:10. 1371/journal.pone.0098819
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0098819
13. The Clinical Spectrum and Treatment of Lyme Disease
ALLEN C. STEERE, M.D., STEPHEN E. MALAWISTA, M.D., NICHOLAS H. BARTENHAGEN, M.D., PHYLLIS N. SPIELER, M.D., JAMES H. NEWMAN, M.D., DANIEL W. RAHN, M.D., GORDON J.HUTCHINSON, M.D., JERRY GREEN, M.D., DAVID R. SNYDMAN, M.D., AND ELISE TAYLOR, B.A
THE YALE JOURNAL OF BIOLOGY AND MEDICINE 57(1984),453-461
www.ncbi.nlm.nih.gov/pmc/articles/PMC2590003/pdf/yjbm00100-0016.pdf
14. Rev Infect Dis. 1989 Sep-Oct;11 Suppl 6:S1518-25.
A perspective on the treatment of Lyme borreliosis.
Luft BJ1, Gorevic PD, Halperin JJ, Volkman DJ, Dattwyler RJ.
www.ncbi.nlm.nih.gov/pubmed/2682965
15. Clinical Pathologic Correlations of Lyme Disease by Stage
PAUL H. DURAY
Department of Pathology
Fox Chase Cancer Center Philadelphia, Pennsylvania 191 I I
ALLEN C. STEERE
Department of Internal Medicine Division of Rheumatology Tufts University School of Medicine Boston, Massachusetts 02111
badlymeattitude.files.wordpress.com/2017/05/steere_duray_1988.pdf
16. The Clinical Spectrum and Treatment of Lyme Disease
ALLEN C. STEERE, M.D., STEPHEN E. MALAWISTA, M.D., NICHOLAS H. BARTENHAGEN, M.D., PHYLLIS N. SPIELER, M.D., JAMES H. NEWMAN, M.D., DANIEL W. RAHN, M.D., GORDON J.HUTCHINSON, M.D., JERRY GREEN, M.D., DAVID R. SNYDMAN, M.D., AND ELISE TAYLOR, B.A. THE YALE JOURNAL OF BIOLOGY AND MEDICINE 57(1984),453-461
www.ncbi.nlm.nih.gov/pmc/articles/PMC2590003/pdf/yjbm00100-0016.pdf
_______________________________________________________
NOTE: All Tuttle family members were eventually diagnosed with late stage chronic Lyme disease and in 2009 featured on the New Hampshire Chronicle episode, “Living with Lyme.” My daughter developed an attention deficit disorder so severe that she could no longer read a chapter and retain what was read. We had to remove her from college and treat her aggressively. My wife could barely walk up a flight of stairs without excruciating knee pain and we thought for certain she would require knee replacement surgery. None of us developed the bulls-eye rash and none of us tested CDC positive using the faulty two-tier FDA approved serology test for Lyme disease. NONE of us!
I have prostate cancer as well; treated with brachytherapy in 2015 and cryoablation in 2018 failing both treatments as PSA is on the rise once again.
Carl Tuttle
Lyme Endemic Hudson, NH
"NOV 18, 2019 —
Today's letter to the Tick-Borne Disease Working Group......
---------- Original Message ----------
From: CARL TUTTLE <runagain@comcast.net>
To: tickbornedisease@hhs.gov, eugene.shapiro@yale.edu
Cc: (98 Undisclosed recipients)
Date: November 18, 2019 at 11:11 AM
Subject: Who is Carl Tuttle?
To: The Tick-Borne Disease Working Group,
ATTN: Eugene Shapiro, MD
The consequences of untreated Lyme disease:
On March 28th 2019 my right kidney was removed (nephrectomy) after a renal scan showed that it was only functioning at 7%. We attempted to save the kidney over the previous 12mo period with a nephrostomy tube by dilating the ureter (Three times unsuccessfully) which was crushed by a large internal lymph node.
Nephrostomy:
www.cirse.org/patients/ir-procedures/nephrostomy/
The swollen lymph node developed as a result of follicular lymphoma which is cancer of the immune system. (Diagnosed in Feb 2017)
In the fall of 2008 I was bedridden, on oxygen and near death after chasing an unresolved fatigue for twelve years. I was ping-ponged through the medical community with deteriorating health and told that I had chronic fatigue syndrome, mitochondrial disease etc. I was forgetting the names of my coworkers of twenty-five years and often did not recognize where I was on my commute home. I was being tested for early Alzheimer's disease. (Similar to Kris Kristofferson)
Carl Tuttle with O2 concentrator:
www.dropbox.com/s/z5918st7pegw4lf/Carl%20Tuttle%20O2%20Concentrator.JPG?dl=0
A Slow Slipping Away Kris Kristofferson’s Long Undiagnosed Battle with Lyme Disease. By Dana Parish
www.lymedisease.org/members/lyme-times/2016-fall-news/kris-kristofferson-lyme-disease/
An astute nurse practitioner advised that I should test for Lyme disease using IGeneX laboratory. Because of the severity of my case it was recommended that I see Dr. Sam Donta of BU School of Medicine who spent a career studying Lyme disease. I Herx’d every day sometimes twice per day for sixteen months. Each time antibiotics were stopped the symptoms would return with a vengeance.
Dr. Donta’s Clinical Notes: (Personal Dropbox storage area)
www.dropbox.com/s/ffvlc9067ei6vd4/Dr%20Donta%20Report%201-26-09.pdf?dl=0
LYME SCI: The dreaded Jarisch-Herxheimer reaction
www.lymedisease.org/lymesci-herxing/
Fast forward to today…. When that large node crushed the right ureter I decided to treat the follicular lymphoma aggressively with Rituxan monotherapy (immunotherapy); my medical claims in 2018 exceeded $600,000. I declined chemotherapy knowing that my immune system was already compromised by the Borrelia infection untreated for twelve years.
Although I uncovered many studies on PubMed noting Borrelia infection together with lymphoma, Dr. Donta felt that my case of lymphoma was more likely a direct result of reactivated Epstein Barr virus which was testing positive on many occasions over the nine years of treatment. A healthy immune system keeps these viruses in check.
Sample EBV lab report: (One of many)
www.dropbox.com/s/iuco0lwurit7a6s/Reactivated%20EBV.JPG?dl=0
Cancer and Infectious Causes
Aaron J. Smith, John Oertle, Dino Prato
Envita, Scottsdale, AZ, USA
Email: Aaron@Envita.com, JohnO@envita.com, DinoPrato@envita.com
Received 4 July 2014; revised 5 August 2014; accepted 4 September 2014
dx.doi.org/10.4236/ojmm.2014.43019
Recently a swollen lymph node in the upper thigh/groin area has returned and a biopsy of that node has identified a more aggressive form of follicular lymphoma. So it looks like the Rituxan has failed. R-CHOP chemotherapy is recommended but the remaining kidney is not functioning at 100% as creatinine levels are elevated and glomerular filtration rate is sub-optimal.
These are the consequences of Lyme disease when the patient is left untreated months, years or decades before diagnosis. But Lyme is a simple “nuisance” disease as dictated by the IDSA and academics that have controlled the narrative for the past thirty years and are now defendants of a racketeering lawsuit in Texas District Court.
Court Document:
www.dropbox.com/s/18uyrli878ug51m/LymeDisease%20RICO%20Lawsuit.pdf?dl=0
What is the motivation for hiding the severity of Lyme disease from the public? Is it just plain ignorance or something more sinister? Lyme disease can be utterly disabling when left untreated but there are no Public Service Announcements informing the public that you could become horribly disabled or die from Lyme disease as exposed in the “Under our Skin” documentary.
Under Our Skin - Extended Trailer (5min video clip)
So I am a Lyme disease victim experiencing exactly what has been outlined (with scientific references) in the following website:
THIS is Lyme
BY BEAUX RELIOSIS on DECEMBER 13, 2017
badlymeattitude.com/2017/12/13/this-is-lyme/
Spirochetes disseminate to the lymph nodes, bone marrow, spleen and brain within a week of infection (1). Lymph node germinal centers, where B cells are supposed to mature and be assigned an immune system function, are rendered incompetent (2). Meanwhile, the toxic triacyl lipoproteins that are shed by spirochetes on blebs of their outer surface get to work causing tolerance and cross tolerance (2,3,4), AKA shutting down the immune system (5,6). There is generalized immune suppression at the same time there are brain inflammation and neurologic complications (7,8,9,10). Opportunistic infections take hold and herpesviruses reactivate (11,12). Half the cases don’t recover fully, regardless of treatment (13,14). The outcome is cancer-like (15, 16).
References: (See personal note at the bottom)
1. Lymphoadenopathy during Lyme Borreliosis Is Caused by Spirochete Migration-Induced Specific B Cell Activation Stefan S. Tunev1,2¤, Christine J. Hastey1,4, Emir Hodzic1, Sunlian Feng1, Stephen W. Barthold, Nicole Baumgarth
www.ncbi.nlm.nih.gov/pmc/articles/PMC3102705/
2. Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection Rebecca A. Elsner, Christine J. Hastey, Kimberly J. Olsen, Nicole Baumgarth Published: July 2, 2015
journals.plos.org/plospathogens/article?id=10.1371%2Fjournal.ppat.1004976
3. J Infect Dis. 2006 Mar 15;193(6):849-59. Epub 2006 Feb 8. Borrelia burgdorferi lipoprotein-mediated TLR2 stimulation causes the down-regulation of TLR5 in human monocytes.
Cabral ES1, Gelderblom H, Hornung RL, Munson PJ, Martin R, Marques AR.
www.ncbi.nlm.nih.gov/pubmed/16479520
4. Borrelia burgdorferi-Induced Tolerance as a Model of Persistence via Immunosuppression
Isabel Diterich1, Carolin Rauter1, Carsten J. Kirschning2 and Thomas Hartung1,*
iai.asm.org/content/71/7/3979.full
5. Lyme Cabal members Gary Wormser and Allen Steere – and even the “CDC officer” Paul Mead – finally admit Late Lyme and LYMErix diseases are immunosuppression outcomes; say “TLR2/1 agonism” (immunosuppression) is probably the “more important” driver of the disease outcome.
Nat Rev Dis Primers. 2016 Dec 15;2:16090. doi: 10.1038/nrdp.2016.90. Lyme borreliosis. Steere AC1,2, Strle F3, Wormser GP4, Hu LT5, Branda JA6, Hovius JW7, Li X8, Mead PS9.
www.ncbi.nlm.nih.gov/pubmed/27976670
6. Seronegative Lyme disease. Dissociation of specific T- and B-lymphocyte responses to Borrelia burgdorferi.
Dattwyler RJ1, Volkman DJ, Luft BJ, Halperin JJ, Thomas J, Golightly MG.
N Engl J Med. 1988 Dec 1;319(22):1441-6.
www.ncbi.nlm.nih.gov/pubmed/3054554
7. Latov, N., Wu, A. T., Chin, R. L., Sander, H. W., Alaedini, A. and Brannagan, T. H. (2004), Neuropathy and cognitive impairment following vaccination with the OspA protein of Borrelia burgdorferi. Journal of the Peripheral Nervous System, 9: 165–167. doi:10.1111/j.1085-9489.2004.09306.x
www.ncbi.nlm.nih.gov/pubmed/15363064
8. Neurological complications of vaccination with outer surface protein A (OspA). Marks DH1. Int J Risk Saf Med. 2011;23(2):89-96. doi: 10.3233/JRS-2011-0527
www.ncbi.nlm.nih.gov/pubmed/21673416
9. J Neuropathol Exp Neurol. 2006 Jun;65(6):540-8. Borrelia burgdorferi Induces TLR1 and TLR2 in human microglia and peripheral blood monocytes but differentially regulates HLA-class II expression.
www.ncbi.nlm.nih.gov/pubmed/16783164
“These results show that signaling through TLR1/2 in response to B. burgdorferi can elicit opposite immunoregulatory effects in blood and in brain immune cells, which could play a role in the different susceptibility of these compartments to infection.”
10. Parthasarathy G, Philipp MT. Receptor tyrosine kinases play a significant role in human oligodendrocyte inflammation and cell death associated with the Lyme disease bacterium Borrelia burgdorferi. Journal of Neuroinflammation. 2017;14:110. doi:10.1186/s12974-017-0883-9.
www.ncbi.nlm.nih.gov/pmc/articles/PMC5450372/
11. Hutchins NA, Unsinger J, Hotchkiss RS, Ayala A. The new normal: immuno-modulatory agents against sepsis immune suppression. Trends in molecular medicine. 2014;20(4):224-233. doi:10.1016/j.molmed.2014.01.002.
www.ncbi.nlm.nih.gov/pmc/articles/PMC3976785/
12. Walton AH, Muenzer JT, Rasche D, Boomer JS, Sato B, et al. (2014) Reactivation of Multiple Viruses in Patients with Sepsis. PLoS ONE 9(6): e98819. doi:10. 1371/journal.pone.0098819
journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0098819
13. The Clinical Spectrum and Treatment of Lyme Disease
ALLEN C. STEERE, M.D., STEPHEN E. MALAWISTA, M.D., NICHOLAS H. BARTENHAGEN, M.D., PHYLLIS N. SPIELER, M.D., JAMES H. NEWMAN, M.D., DANIEL W. RAHN, M.D., GORDON J.HUTCHINSON, M.D., JERRY GREEN, M.D., DAVID R. SNYDMAN, M.D., AND ELISE TAYLOR, B.A
THE YALE JOURNAL OF BIOLOGY AND MEDICINE 57(1984),453-461
www.ncbi.nlm.nih.gov/pmc/articles/PMC2590003/pdf/yjbm00100-0016.pdf
14. Rev Infect Dis. 1989 Sep-Oct;11 Suppl 6:S1518-25.
A perspective on the treatment of Lyme borreliosis.
Luft BJ1, Gorevic PD, Halperin JJ, Volkman DJ, Dattwyler RJ.
www.ncbi.nlm.nih.gov/pubmed/2682965
15. Clinical Pathologic Correlations of Lyme Disease by Stage
PAUL H. DURAY
Department of Pathology
Fox Chase Cancer Center Philadelphia, Pennsylvania 191 I I
ALLEN C. STEERE
Department of Internal Medicine Division of Rheumatology Tufts University School of Medicine Boston, Massachusetts 02111
badlymeattitude.files.wordpress.com/2017/05/steere_duray_1988.pdf
16. The Clinical Spectrum and Treatment of Lyme Disease
ALLEN C. STEERE, M.D., STEPHEN E. MALAWISTA, M.D., NICHOLAS H. BARTENHAGEN, M.D., PHYLLIS N. SPIELER, M.D., JAMES H. NEWMAN, M.D., DANIEL W. RAHN, M.D., GORDON J.HUTCHINSON, M.D., JERRY GREEN, M.D., DAVID R. SNYDMAN, M.D., AND ELISE TAYLOR, B.A. THE YALE JOURNAL OF BIOLOGY AND MEDICINE 57(1984),453-461
www.ncbi.nlm.nih.gov/pmc/articles/PMC2590003/pdf/yjbm00100-0016.pdf
_______________________________________________________
NOTE: All Tuttle family members were eventually diagnosed with late stage chronic Lyme disease and in 2009 featured on the New Hampshire Chronicle episode, “Living with Lyme.” My daughter developed an attention deficit disorder so severe that she could no longer read a chapter and retain what was read. We had to remove her from college and treat her aggressively. My wife could barely walk up a flight of stairs without excruciating knee pain and we thought for certain she would require knee replacement surgery. None of us developed the bulls-eye rash and none of us tested CDC positive using the faulty two-tier FDA approved serology test for Lyme disease. NONE of us!
I have prostate cancer as well; treated with brachytherapy in 2015 and cryoablation in 2018 failing both treatments as PSA is on the rise once again.
Carl Tuttle
Lyme Endemic Hudson, NH